Atypical Infection-Related Glomerulonephritis With “Masked” IgG-Kappa Crystalline Hump-Like Deposits
نویسندگان
چکیده
منابع مشابه
Clinicopathologic Features of Membranous-Like Glomerulopathy With Masked IgG Kappa Deposits
The diagnostic classification of glomerulonephritis is determined by the interplay of changes seen using light, immunofluorescence, and electron microscopy of the renal biopsy. Routine direct immunofluorescence on fresh tissue is currently considered the gold standard for the detection and characterization of immune deposits. We recently found a peculiar form of glomerular immune complex deposi...
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The diagnosis of membranoproliferative glomerulonephritis (MPGN) has recently undergone change from an electron microscopy-based classification scheme to one based largely on immunofluorescence findings. This change is due to the recognition that many of these cases are driven by abnormalities of the alternative complement cascade, resulting in the concept of C3 glomerulopathy. Here we reviewed...
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Dysproteinemias that result in monoclonal glomerular deposits of IgG are relatively uncommon. Here, we report the largest series of proliferative glomerulonephritis with monoclonal IgG deposits, a form of renal involvement by monoclonal gammopathy that mimics immune-complex glomerulonephritis. We retrospectively identified 37 patients, most of whom were white (81%), female (62%), or older than ...
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Anjuman Howlader, Bijin Thajudeen, Amy N. Sussman, Erika Bracamonte, Leslie Krahl and Samih H. Nasr Department of Nephrology, Banner University of Arizona Medical Center, Tucson, AZ, USA; Department of Pathology, Banner University of Arizona Medical Center, Tucson, AZ, USA; Department of Pathology, Banner University Medical Center, Phoenix, AZ, USA; and Department of Laboratory Medicine and Pat...
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BACKGROUND AND OBJECTIVES Proliferative GN with monoclonal IgG deposits (PGNMID) is a newly described entity resembling immune complex GN. Its potential to recur in the allograft is undefined. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS The first cases of recurrent PGNMID in the allograft are reported. RESULTS The cohort includes four Caucasians (3 women, 1 man) with a mean age 58.5 years...
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ژورنال
عنوان ژورنال: Kidney International Reports
سال: 2021
ISSN: 2468-0249
DOI: 10.1016/j.ekir.2020.10.018